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KMID : 0388220100170020177
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Journal of the Korean Rheumatism Association
2010 Volume.17 No. 2 p.177 ~ p.182
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Posterior Reversible Encephalopathy Syndrome in a Patient with Lupus Nephritis
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Kim Hyun-Kyung
Kim Hyoun-Ah
Jang Eun-Jung
Suh Chang-Hee
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Abstract
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Posterior reversible encephalopathy syndrome (PRES) has been described in various clinical settings, including severe hypertension, eclampsia, lupus and immunosuppressive therapy. We report a 27 year-old female systemic lupus erythematosus patient who developed severe headache, seizure and hemiparesis during her lupus nephritis flare. Magnetic resonance image (MRI) showed multi-focal high signal intensity lesions in the parieto-occipital cortex bilaterally and in the subcortical white matter. Her condition improved with immunosuppressive treatments, antihypertensives and hemodialysis. The extent of her lesions decreased on follow-up MRI 2 months later. This case suggests that PRES can be treated with immunosuppressive drugs that do not increase blood pressure.
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KEYWORD
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Systemic lupus erythematosus, Posterior reversible encephalopathy syndrome, Lupus nephritis
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